L583-0038 Screening compound: N-[8-fluoro-2-(pyrrolidin-1-yl)quinolin-6-yl]-4-methylbenzamide

L583-0038 Screening compound: N-[8-fluoro-2-(pyrrolidin-1-yl)quinolin-6-yl]-4-methylbenzamide
L583-0038 Screening compound: N-[8-fluoro-2-(pyrrolidin-1-yl)quinolin-6-yl]-4-methylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L583-0038
N-[8-fluoro-2-(pyrrolidin-1-yl)quinolin-6-yl]-4-methylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L583-0038

Molecular Formula

C21H20FN3O (C21 H20 FN3 O)

Compound Name

N-[8-fluoro-2-(pyrrolidin-1-yl)quinolin-6-yl]-4-methylbenzamide

IUPAC name

N-[8-fluoro-2-(pyrrolidin-1-yl)quinolin-6-yl]-4-methylbenzamide

SMILES

Cc(cc1)ccc1C(Nc1cc2ccc(N3CCCC3)nc2c(F)c1)=O

InChI

InChI=1S/C21H20FN3O/c1-14-4-6-15(7-5-14)21(26)23-17-12-16-8-9-19(25-10-2-3-11-25)24-20(16)18(22)13-17/h4-9,12-13H,2-3,10-11H2,1H3,(H,23,26)

InChI Key

NAZCFZJLAXXAMF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15131133

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

349.41

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.064

Distribution Coefficient, logD

5.059

Water Solubility, LogSw

-4.96

Polar Surface Area

35.713

Acid Dissociation Constant (pKa)

9.35

Base Dissociation Constant (pKb)

3.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

L583-0038 in Drug Discovery

Included in Screening Libraries

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L583-0038 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L583-0038?
Check Price and Availability of L583-0038, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L583-0038 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L583-0038
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L583-0038
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L583-0038 available by request