L586-1409 Screening compound: 2-chloro-N-[2-(1H-indol-3-yl)ethyl]-5-(thiomorpholine-4-sulfonyl)benzamide

L586-1409 Screening compound: 2-chloro-N-[2-(1H-indol-3-yl)ethyl]-5-(thiomorpholine-4-sulfonyl)benzamide
L586-1409 Screening compound: 2-chloro-N-[2-(1H-indol-3-yl)ethyl]-5-(thiomorpholine-4-sulfonyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L586-1409
2-chloro-N-[2-(1H-indol-3-yl)ethyl]-5-(thiomorpholine-4-sulfonyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L586-1409

Molecular Formula

C21H22ClN3O3S2 (C21 H22 ClN3 O3 S2)

Compound Name

2-chloro-N-[2-(1H-indol-3-yl)ethyl]-5-(thiomorpholine-4-sulfonyl)benzamide

IUPAC name

2-chloro-N-[2-(1H-indol-3-yl)ethyl]-5-(thiomorpholine-4-sulfonyl)benzamide

SMILES

O=C(c(cc(cc1)S(N2CCSCC2)(=O)=O)c1Cl)NCCc1c[nH]c2c1cccc2

InChI

InChI=1S/C21H22ClN3O3S2/c22-19-6-5-16(30(27,28)25-9-11-29-12-10-25)13-18(19)21(26)23-8-7-15-14-24-20-4-2-1-3-17(15)20/h1-6,13-14,24H,7-12H2,(H,23,26)

InChI Key

OQFSATILIALULW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27463951

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.01

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.739

Distribution Coefficient, logD

3.739

Water Solubility, LogSw

-4.36

Polar Surface Area

66.075

Acid Dissociation Constant (pKa)

11.41

Base Dissociation Constant (pKb)

-3.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

L586-1409 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

Lipid Metabolism Library (9174 compounds)

PLpro Library (6343 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cardiovascular
  • Metabolic
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L586-1409 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L586-1409?
Check Price and Availability of L586-1409, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L586-1409 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L586-1409
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L586-1409
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L586-1409 available by request