L588-0028 Screening compound: 1-[4-(1H-indole-2-carbonyl)piperazin-1-yl]-3-(4-methoxyphenyl)propan-1-one

L588-0028 Screening compound: 1-[4-(1H-indole-2-carbonyl)piperazin-1-yl]-3-(4-methoxyphenyl)propan-1-one
L588-0028 Screening compound: 1-[4-(1H-indole-2-carbonyl)piperazin-1-yl]-3-(4-methoxyphenyl)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L588-0028
1-[4-(1H-indole-2-carbonyl)piperazin-1-yl]-3-(4-methoxyphenyl)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L588-0028

Molecular Formula

C23H25N3O3 (C23 H25 N3 O3)

Compound Name

1-[4-(1H-indole-2-carbonyl)piperazin-1-yl]-3-(4-methoxyphenyl)propan-1-one

IUPAC name

1-[4-(1H-indole-2-carbonyl)piperazin-1-yl]-3-(4-methoxyphenyl)propan-1-one

SMILES

COc1ccc(CCC(N(CC2)CCN2C(c2cc(cccc3)c3[nH]2)=O)=O)cc1

InChI

InChI=1S/C23H25N3O3/c1-29-19-9-6-17(7-10-19)8-11-22(27)25-12-14-26(15-13-25)23(28)21-16-18-4-2-3-5-20(18)24-21/h2-7,9-10,16,24H,8,11-15H2,1H3

InChI Key

HMFDGWWLHVRREM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09854000

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

391.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.457

Distribution Coefficient, logD

3.457

Water Solubility, LogSw

-3.71

Polar Surface Area

49.708

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

-1.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

L588-0028 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Proteases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L588-0028 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L588-0028?
Check Price and Availability of L588-0028, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L588-0028 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L588-0028
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L588-0028
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L588-0028 available by request