L589-1177 Screening compound: N-[1-(4-fluorophenyl)ethyl]-1-[(1-methyl-1H-indol-3-yl)methyl]piperidine-4-carboxamide

L589-1177 Screening compound: N-[1-(4-fluorophenyl)ethyl]-1-[(1-methyl-1H-indol-3-yl)methyl]piperidine-4-carboxamide
L589-1177 Screening compound: N-[1-(4-fluorophenyl)ethyl]-1-[(1-methyl-1H-indol-3-yl)methyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L589-1177
N-[1-(4-fluorophenyl)ethyl]-1-[(1-methyl-1H-indol-3-yl)methyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L589-1177

Molecular Formula

C24H28FN3O (C24 H28 FN3 O)

Compound Name

N-[1-(4-fluorophenyl)ethyl]-1-[(1-methyl-1H-indol-3-yl)methyl]piperidine-4-carboxamide

IUPAC name

N-[1-(4-fluorophenyl)ethyl]-1-[(1-methyl-1H-indol-3-yl)methyl]piperidine-4-carboxamide

SMILES

CC(c(cc1)ccc1F)NC(C1CCN(Cc2cn(C)c3c2cccc3)CC1)=O

InChI

InChI=1S/C24H28FN3O/c1-17(18-7-9-21(25)10-8-18)26-24(29)19-11-13-28(14-12-19)16-20-15-27(2)23-6-4-3-5-22(20)23/h3-10,15,17,19H,11-14,16H2,1-2H3,(H,26,29)/t17-/m0/s1

InChI Key

UGBNHZMASYKORJ-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27464124

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.5

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.343

Distribution Coefficient, logD

-1.645

Water Solubility, LogSw

-3.29

Polar Surface Area

30.107

Acid Dissociation Constant (pKa)

12.12

Base Dissociation Constant (pKb)

11.41

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.50

L589-1177 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

CORONAVIRUS Library (20774 compounds)

Indole Derivatives (10091 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

PLpro Library (6343 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Structure:
  • Cyclic compounds
  • Cyclic compounds
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L589-1177 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L589-1177?
Check Price and Availability of L589-1177, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L589-1177 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L589-1177
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L589-1177
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L589-1177 available by request