L589-1206 Screening compound: 1-[(1-methyl-1H-indol-3-yl)methyl]-N-[2-(4-phenylpiperazin-1-yl)ethyl]piperidine-4-carboxamide

L589-1206 Screening compound: 1-[(1-methyl-1H-indol-3-yl)methyl]-N-[2-(4-phenylpiperazin-1-yl)ethyl]piperidine-4-carboxamide
L589-1206 Screening compound: 1-[(1-methyl-1H-indol-3-yl)methyl]-N-[2-(4-phenylpiperazin-1-yl)ethyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L589-1206
1-[(1-methyl-1H-indol-3-yl)methyl]-N-[2-(4-phenylpiperazin-1-yl)ethyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L589-1206

Molecular Formula

C28H37N5O (C28 H37 N5 O)

Compound Name

1-[(1-methyl-1H-indol-3-yl)methyl]-N-[2-(4-phenylpiperazin-1-yl)ethyl]piperidine-4-carboxamide

IUPAC name

1-[(1-methyl-1H-indol-3-yl)methyl]-N-[2-(4-phenylpiperazin-1-yl)ethyl]piperidine-4-carboxamide

SMILES

Cn1c(cccc2)c2c(CN(CC2)CCC2C(NCCN(CC2)CCN2c2ccccc2)=O)c1

InChI

InChI=1S/C28H37N5O/c1-30-21-24(26-9-5-6-10-27(26)30)22-32-14-11-23(12-15-32)28(34)29-13-16-31-17-19-33(20-18-31)25-7-3-2-4-8-25/h2-10,21,23H,11-20,22H2,1H3,(H,29,34)

InChI Key

OFSHITKFLOZQGA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27464129

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.63

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.004

Distribution Coefficient, logD

-1.983

Water Solubility, LogSw

-2.94

Polar Surface Area

38.028

Acid Dissociation Constant (pKa)

13.35

Base Dissociation Constant (pKb)

12.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.40

L589-1206 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

CORONAVIRUS Library (20774 compounds)

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

PLpro Library (6343 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L589-1206 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L589-1206?
Check Price and Availability of L589-1206, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L589-1206 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L589-1206
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L589-1206
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L589-1206 available by request