L605-0045 Screening compound: 7-(3-chloro-4-fluorophenyl)-2-(2,4-difluorophenyl)-7H,8H-imidazo[1,2-a]pyrazin-8-one

L605-0045 Screening compound: 7-(3-chloro-4-fluorophenyl)-2-(2,4-difluorophenyl)-7H,8H-imidazo[1,2-a]pyrazin-8-one
L605-0045 Screening compound: 7-(3-chloro-4-fluorophenyl)-2-(2,4-difluorophenyl)-7H,8H-imidazo[1,2-a]pyrazin-8-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L605-0045
7-(3-chloro-4-fluorophenyl)-2-(2,4-difluorophenyl)-7H,8H-imidazo[1,2-a]pyrazin-8-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L605-0045

Molecular Formula

C18H9ClF3N3O (C18 H9 ClF3 N3 O)

Compound Name

7-(3-chloro-4-fluorophenyl)-2-(2,4-difluorophenyl)-7H,8H-imidazo[1,2-a]pyrazin-8-one

IUPAC name

7-(3-chloro-4-fluorophenyl)-2-(24-difluorophenyl)-7H8H-imidazo[12-a]pyrazin-8-one

SMILES

O=C(c1nc(-c(ccc(F)c2)c2F)cn1C=C1)N1c(cc1)cc(Cl)c1F

InChI

InChI=1S/C18H9ClF3N3O/c19-13-8-11(2-4-14(13)21)25-6-5-24-9-16(23-17(24)18(25)26)12-3-1-10(20)7-15(12)22/h1-9H

InChI Key

SMCHWELNAPICRV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27464819

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.74

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.528

Distribution Coefficient, logD

3.528

Water Solubility, LogSw

-3.98

Polar Surface Area

26.031

Acid Dissociation Constant (pKa)

14.00

Base Dissociation Constant (pKb)

-1.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

L605-0045 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L605-0045 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L605-0045?
Check Price and Availability of L605-0045, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L605-0045 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L605-0045
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L605-0045
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L605-0045 available by request