L606-0394 Screening compound: 1-(3-fluoro-4-methylphenyl)-3-{3-oxo-4-[4-(propan-2-yl)phenyl]-3,4-dihydropyrazin-2-yl}urea

L606-0394 Screening compound: 1-(3-fluoro-4-methylphenyl)-3-{3-oxo-4-[4-(propan-2-yl)phenyl]-3,4-dihydropyrazin-2-yl}urea
L606-0394 Screening compound: 1-(3-fluoro-4-methylphenyl)-3-{3-oxo-4-[4-(propan-2-yl)phenyl]-3,4-dihydropyrazin-2-yl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L606-0394
1-(3-fluoro-4-methylphenyl)-3-{3-oxo-4-[4-(propan-2-yl)phenyl]-3,4-dihydropyrazin-2-yl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L606-0394

Molecular Formula

C21H21FN4O2 (C21 H21 FN4 O2)

Compound Name

1-(3-fluoro-4-methylphenyl)-3-{3-oxo-4-[4-(propan-2-yl)phenyl]-3,4-dihydropyrazin-2-yl}urea

IUPAC name

1-(3-fluoro-4-methylphenyl)-3-{3-oxo-4-[4-(propan-2-yl)phenyl]-34-dihydropyrazin-2-yl}urea

SMILES

CC(C)c(cc1)ccc1N(C=CN=C1NC(Nc2cc(F)c(C)cc2)=O)C1=O

InChI

InChI=1S/C21H21FN4O2/c1-13(2)15-5-8-17(9-6-15)26-11-10-23-19(20(26)27)25-21(28)24-16-7-4-14(3)18(22)12-16/h4-13H,1-3H3,(H2,23,24,25,28)

InChI Key

CSDROCXHAIDPIF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27465230

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.991

Distribution Coefficient, logD

3.463

Water Solubility, LogSw

-4.13

Polar Surface Area

57.370

Acid Dissociation Constant (pKa)

7.03

Base Dissociation Constant (pKb)

0.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

L606-0394 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L606-0394 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L606-0394?
Check Price and Availability of L606-0394, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L606-0394 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L606-0394
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L606-0394
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L606-0394 available by request