L609-0153 Screening compound: 3-[2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]-1-(piperidin-1-yl)propan-1-one

L609-0153 Screening compound: 3-[2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]-1-(piperidin-1-yl)propan-1-one
L609-0153 Screening compound: 3-[2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]-1-(piperidin-1-yl)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L609-0153
3-[2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]-1-(piperidin-1-yl)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L609-0153

Molecular Formula

C21H22FN3O (C21 H22 FN3 O)

Compound Name

3-[2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]-1-(piperidin-1-yl)propan-1-one

IUPAC name

3-[2-(4-fluorophenyl)imidazo[12-a]pyridin-3-yl]-1-(piperidin-1-yl)propan-1-one

SMILES

O=C(CCc1c(-c(cc2)ccc2F)nc2n1cccc2)N1CCCCC1

InChI

InChI=1S/C21H22FN3O/c22-17-9-7-16(8-10-17)21-18(25-15-5-2-6-19(25)23-21)11-12-20(26)24-13-3-1-4-14-24/h2,5-10,15H,1,3-4,11-14H2

InChI Key

LXAULTLKSMMWQZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27465515

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.42

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.177

Distribution Coefficient, logD

3.176

Water Solubility, LogSw

-3.21

Polar Surface Area

24.726

Acid Dissociation Constant (pKa)

23.16

Base Dissociation Constant (pKb)

4.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L609-0153 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

GABA Library (7115 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Eye
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with L609-0153 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L609-0153?
Check Price and Availability of L609-0153, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L609-0153 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L609-0153
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L609-0153
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L609-0153 available by request