L627-1114 Screening compound: 5-({4-[(BUTAN-2-YL)CARBAMOYL]PHENYL}METHYL)-1-METHYL-N-PHENYL-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDINE-3-CARBOXAMIDE

L627-1114 Screening compound: 5-({4-[(BUTAN-2-YL)CARBAMOYL]PHENYL}METHYL)-1-METHYL-N-PHENYL-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDINE-3-CARBOXAMIDE
L627-1114 Screening compound: 5-({4-[(BUTAN-2-YL)CARBAMOYL]PHENYL}METHYL)-1-METHYL-N-PHENYL-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDINE-3-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L627-1114
5-({4-[(BUTAN-2-YL)CARBAMOYL]PHENYL}METHYL)-1-METHYL-N-PHENYL-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDINE-3-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L627-1114

Molecular Formula

C26H31N5O2 (C26 H31 N5 O2)

Compound Name

5-({4-[(BUTAN-2-YL)CARBAMOYL]PHENYL}METHYL)-1-METHYL-N-PHENYL-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDINE-3-CARBOXAMIDE

IUPAC name

n/a

SMILES

CCC(C)NC(c1ccc(CN(CC2)Cc3c2n(C)nc3C(Nc2ccccc2)=O)cc1)=O

InChI

InChI=1S/C26H31N5O2/c1-4-18(2)27-25(32)20-12-10-19(11-13-20)16-31-15-14-23-22(17-31)24(29-30(23)3)26(33)28-21-8-6-5-7-9-21/h5-13,18H,4,14-17H2,1-3H3,(H,27,32)(H,28,33)/t18-/m0/s1

InChI Key

RMHXGIJBKQRBJF-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27466136

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.56

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.496

Distribution Coefficient, logD

-2.184

Water Solubility, LogSw

-2.83

Polar Surface Area

65.868

Acid Dissociation Constant (pKa)

11.66

Base Dissociation Constant (pKb)

11.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

34.60

L627-1114 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with L627-1114 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L627-1114?
Check Price and Availability of L627-1114, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L627-1114 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L627-1114
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L627-1114
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L627-1114 available by request