L628-0007 Screening compound: 2-{1-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]piperidin-4-yl}-N-[(pyridin-2-yl)methyl]acetamide

L628-0007 Screening compound: 2-{1-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]piperidin-4-yl}-N-[(pyridin-2-yl)methyl]acetamide
L628-0007 Screening compound: 2-{1-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]piperidin-4-yl}-N-[(pyridin-2-yl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L628-0007
2-{1-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]piperidin-4-yl}-N-[(pyridin-2-yl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L628-0007

Molecular Formula

C18H24N4O4S (C18 H24 N4 O4 S)

Compound Name

2-{1-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]piperidin-4-yl}-N-[(pyridin-2-yl)methyl]acetamide

IUPAC name

2-{1-[(35-dimethyl-12-oxazol-4-yl)sulfonyl]piperidin-4-yl}-N-[(pyridin-2-yl)methyl]acetamide

SMILES

Cc1noc(C)c1S(N1CCC(CC(NCc2ncccc2)=O)CC1)(=O)=O

InChI

InChI=1S/C18H24N4O4S/c1-13-18(14(2)26-21-13)27(24,25)22-9-6-15(7-10-22)11-17(23)20-12-16-5-3-4-8-19-16/h3-5,8,15H,6-7,9-12H2,1-2H3,(H,20,23)

InChI Key

ZMYRWLPBXAJRQG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27466151

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.48

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.956

Distribution Coefficient, logD

0.956

Water Solubility, LogSw

-2.36

Polar Surface Area

87.731

Acid Dissociation Constant (pKa)

12.62

Base Dissociation Constant (pKb)

4.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L628-0007 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L628-0007 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L628-0007?
Check Price and Availability of L628-0007, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L628-0007 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L628-0007
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L628-0007
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L628-0007 available by request