L628-0441 Screening compound: 2-{1-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]piperidin-4-yl}-N-[(4-methoxyphenyl)methyl]propanamide

L628-0441 Screening compound: 2-{1-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]piperidin-4-yl}-N-[(4-methoxyphenyl)methyl]propanamide
L628-0441 Screening compound: 2-{1-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]piperidin-4-yl}-N-[(4-methoxyphenyl)methyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L628-0441
2-{1-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]piperidin-4-yl}-N-[(4-methoxyphenyl)methyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L628-0441

Molecular Formula

C21H29N3O5S (C21 H29 N3 O5 S)

Compound Name

2-{1-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]piperidin-4-yl}-N-[(4-methoxyphenyl)methyl]propanamide

IUPAC name

2-{1-[(35-dimethyl-12-oxazol-4-yl)sulfonyl]piperidin-4-yl}-N-[(4-methoxyphenyl)methyl]propanamide

SMILES

CC(C(CC1)CCN1S(c1c(C)onc1C)(=O)=O)C(NCc(cc1)ccc1OC)=O

InChI

InChI=1S/C21H29N3O5S/c1-14(21(25)22-13-17-5-7-19(28-4)8-6-17)18-9-11-24(12-10-18)30(26,27)20-15(2)23-29-16(20)3/h5-8,14,18H,9-13H2,1-4H3,(H,22,25)/t14-/m0/s1

InChI Key

ZNPMGGBTVXPXGN-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD27466220

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.54

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.744

Distribution Coefficient, logD

1.744

Water Solubility, LogSw

-2.50

Polar Surface Area

85.945

Acid Dissociation Constant (pKa)

13.57

Base Dissociation Constant (pKb)

-2.18

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.40

L628-0441 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L628-0441 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L628-0441?
Check Price and Availability of L628-0441, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L628-0441 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L628-0441
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L628-0441
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L628-0441 available by request