L629-0756 Screening compound: 2-{1-[(5-chlorothiophen-2-yl)sulfonyl]piperidin-4-yl}-1-[4-(pyrimidin-2-yl)piperazin-1-yl]ethan-1-one

L629-0756 Screening compound: 2-{1-[(5-chlorothiophen-2-yl)sulfonyl]piperidin-4-yl}-1-[4-(pyrimidin-2-yl)piperazin-1-yl]ethan-1-one
L629-0756 Screening compound: 2-{1-[(5-chlorothiophen-2-yl)sulfonyl]piperidin-4-yl}-1-[4-(pyrimidin-2-yl)piperazin-1-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L629-0756
2-{1-[(5-chlorothiophen-2-yl)sulfonyl]piperidin-4-yl}-1-[4-(pyrimidin-2-yl)piperazin-1-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L629-0756

Molecular Formula

C19H24ClN5O3S2 (C19 H24 ClN5 O3 S2)

Compound Name

2-{1-[(5-chlorothiophen-2-yl)sulfonyl]piperidin-4-yl}-1-[4-(pyrimidin-2-yl)piperazin-1-yl]ethan-1-one

IUPAC name

2-{1-[(5-chlorothiophen-2-yl)sulfonyl]piperidin-4-yl}-1-[4-(pyrimidin-2-yl)piperazin-1-yl]ethan-1-one

SMILES

O=C(CC(CC1)CCN1S(c(s1)ccc1Cl)(=O)=O)N(CC1)CCN1c1ncccn1

InChI

InChI=1S/C19H24ClN5O3S2/c20-16-2-3-18(29-16)30(27,28)25-8-4-15(5-9-25)14-17(26)23-10-12-24(13-11-23)19-21-6-1-7-22-19/h1-3,6-7,15H,4-5,8-14H2

InChI Key

CLOBRMCJWCFFDD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27466489

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.02

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.984

Distribution Coefficient, logD

2.984

Water Solubility, LogSw

-3.31

Polar Surface Area

70.711

Acid Dissociation Constant (pKa)

21.15

Base Dissociation Constant (pKb)

2.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.60

L629-0756 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L629-0756 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L629-0756?
Check Price and Availability of L629-0756, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L629-0756 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L629-0756
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L629-0756
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L629-0756 available by request