L632-0848 Screening compound: 1-{[5-(cyclobutylcarbonyl)-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]carbonyl}-N~3~,N~3~-diethyl-3-piperidinecarboxamide

Chemical Structure Depiction of ChemDiv screening compound L632-0848
1-{[5-(cyclobutylcarbonyl)-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]carbonyl}-N~3~,N~3~-diethyl-3-piperidinecarboxamide

Available from 1 mg

Formats:

Glass Vials (4ml Glass Vials VWR #97047-678)
96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

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Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L632-0848

Molecular Formula

C₂₃H₃₅N₅O₃ (C23 H35 N5 O3)

Compound Name

1-{[5-(cyclobutylcarbonyl)-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]carbonyl}-N~3~,N~3~-diethyl-3-piperidinecarboxamide

IUPAC name

1-{5-cyclobutanecarbonyl-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridine-3-carbonyl}-NN-diethylpiperidine-3-carboxamide

SMILES

CCN(CC)C(C(CCC1)CN1C(c1nn(C)c(CC2)c1CN2C(C1CCC1)=O)=O)=O

InChI

InChI=1S/C23H35N5O3/c1-4-26(5-2)22(30)17-10-7-12-27(14-17)23(31)20-18-15-28(21(29)16-8-6-9-16)13-11-19(18)25(3)24-20/h16-17H,4-15H2,1-3H3/t17-/m0/s1

InChI Key

QPAXHTSQAWWDSE-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27466723

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.56

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

Partition Coefficient, logP

0.486

Distribution Coefficient, logD

0.485

Water Solubility, LogSw

-0.22

Polar Surface Area

64.603

Acid Dissociation Constant (pK_a)

22.78

Base Dissociation Constant (pK_b)

3.57

Number of Chiral Centers

1.00

Percent sp³ carbon bonding

73.91

L632-0848 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

GPCR Targeted Library (31838 compounds)

Hsp90-Targeted Library (11355 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:

Cancer
Infections
Cancer
Musculoskeletal
Digestive system
Nervous system
Cardiovascular
Skin
Metabolic
Endocrine
Immune system
Musculoskeletal
Respiratory tract
Nervous system
Congenital
Skin
Metabolic
Endocrine
Cancer
Digestive system
Respiratory tract
Male
Female
Hemic and lymphatic
Immune system

Targets:

Proteases
GPCR

Mechanism of action:

Receptor's ligands
PPI modulators
PPI modulators

Structure:

Mimetics

References: we are preparing a list of scientific research reports with L632-0848 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L632-0848?
Check Price and Availability of L632-0848, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.

What is the minimum amount of L632-0848 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.

Delivery options for L632-0848
ChemDiv sends parcels with Express services (UPS, WC).

1–2 days for small orders
2–4 weeks for large selections

Delivery formats for L632-0848

0.5–50 mg of dry powder sample in single glass vials, custom vials
DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L632-0848 available by request