L632-0858 Screening compound: N,N-diethyl-1-{5-[2-(4-methoxyphenyl)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}piperidine-3-carboxamide

L632-0858 Screening compound: N,N-diethyl-1-{5-[2-(4-methoxyphenyl)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}piperidine-3-carboxamide
L632-0858 Screening compound: N,N-diethyl-1-{5-[2-(4-methoxyphenyl)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L632-0858
N,N-diethyl-1-{5-[2-(4-methoxyphenyl)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L632-0858

Molecular Formula

C27H37N5O4 (C27 H37 N5 O4)

Compound Name

N,N-diethyl-1-{5-[2-(4-methoxyphenyl)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}piperidine-3-carboxamide

IUPAC name

NN-diethyl-1-{5-[2-(4-methoxyphenyl)acetyl]-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridine-3-carbonyl}piperidine-3-carboxamide

SMILES

CCN(CC)C(C(CCC1)CN1C(c1nn(C)c(CC2)c1CN2C(Cc(cc1)ccc1OC)=O)=O)=O

InChI

InChI=1S/C27H37N5O4/c1-5-30(6-2)26(34)20-8-7-14-32(17-20)27(35)25-22-18-31(15-13-23(22)29(3)28-25)24(33)16-19-9-11-21(36-4)12-10-19/h9-12,20H,5-8,13-18H2,1-4H3/t20-/m0/s1

InChI Key

QGFRYWXFOHZLAC-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD27466726

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

495.62

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.508

Distribution Coefficient, logD

1.508

Water Solubility, LogSw

-1.98

Polar Surface Area

71.097

Acid Dissociation Constant (pKa)

17.36

Base Dissociation Constant (pKb)

3.51

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

55.60

L632-0858 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with L632-0858 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L632-0858?
Check Price and Availability of L632-0858, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L632-0858 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L632-0858
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L632-0858
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L632-0858 available by request