L632-1081 Screening compound: N-cyclopropyl-1-[1-methyl-5-(3-phenylpropanoyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl]piperidine-3-carboxamide

Chemical Structure Depiction of ChemDiv screening compound L632-1081
N-cyclopropyl-1-[1-methyl-5-(3-phenylpropanoyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

Glass Vials (4ml Glass Vials VWR #97047-678)
96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

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Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L632-1081

Molecular Formula

C₂₆H₃₃N₅O₃ (C26 H33 N5 O3)

Compound Name

N-cyclopropyl-1-[1-methyl-5-(3-phenylpropanoyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl]piperidine-3-carboxamide

IUPAC name

N-cyclopropyl-1-[1-methyl-5-(3-phenylpropanoyl)-1H4H5H6H7H-pyrazolo[43-c]pyridine-3-carbonyl]piperidine-3-carboxamide

SMILES

Cn1nc(C(N(CCC2)CC2C(NC2CC2)=O)=O)c(C2)c1CCN2C(CCc1ccccc1)=O

InChI

InChI=1S/C26H33N5O3/c1-29-22-13-15-30(23(32)12-9-18-6-3-2-4-7-18)17-21(22)24(28-29)26(34)31-14-5-8-19(16-31)25(33)27-20-10-11-20/h2-4,6-7,19-20H,5,8-17H2,1H3,(H,27,33)/t19-/m0/s1

InChI Key

KUBWNBRCYJOIGY-IBGZPJMESA-N

MDL Number (MFCD)

MFCD27466752

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.58

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

Partition Coefficient, logP

1.248

Distribution Coefficient, logD

1.248

Water Solubility, LogSw

-1.91

Polar Surface Area

72.090

Acid Dissociation Constant (pK_a)

13.13

Base Dissociation Constant (pK_b)

10.39

Number of Chiral Centers

1.00

Percent sp³ carbon bonding

53.80

L632-1081 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:

Cancer
Infections
Cancer
Musculoskeletal
Digestive system
Nervous system
Cardiovascular
Skin
Metabolic
Endocrine
Immune system
Cancer
Digestive system
Respiratory tract
Male
Female
Hemic and lymphatic
Immune system

Targets:

Proteases

Mechanism of action:

PPI modulators
PPI modulators
PPI modulators
PPI modulators

Structure:

Mimetics
Mimetics
Mimetics

References: we are preparing a list of scientific research reports with L632-1081 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L632-1081?
Check Price and Availability of L632-1081, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.

What is the minimum amount of L632-1081 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.

Delivery options for L632-1081
ChemDiv sends parcels with Express services (UPS, WC).

1–2 days for small orders
2–4 weeks for large selections

Delivery formats for L632-1081

0.5–50 mg of dry powder sample in single glass vials, custom vials
DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L632-1081 available by request