L632-1083 Screening compound: 1-{5-[2-(4-chlorophenyl)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}-N-cyclopropylpiperidine-3-carboxamide

L632-1083 Screening compound: 1-{5-[2-(4-chlorophenyl)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}-N-cyclopropylpiperidine-3-carboxamide
L632-1083 Screening compound: 1-{5-[2-(4-chlorophenyl)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}-N-cyclopropylpiperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L632-1083
1-{5-[2-(4-chlorophenyl)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}-N-cyclopropylpiperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L632-1083

Molecular Formula

C25H30ClN5O3 (C25 H30 ClN5 O3)

Compound Name

1-{5-[2-(4-chlorophenyl)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}-N-cyclopropylpiperidine-3-carboxamide

IUPAC name

1-{5-[2-(4-chlorophenyl)acetyl]-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridine-3-carbonyl}-N-cyclopropylpiperidine-3-carboxamide

SMILES

Cn1nc(C(N(CCC2)CC2C(NC2CC2)=O)=O)c(C2)c1CCN2C(Cc(cc1)ccc1Cl)=O

InChI

InChI=1S/C25H30ClN5O3/c1-29-21-10-12-30(22(32)13-16-4-6-18(26)7-5-16)15-20(21)23(28-29)25(34)31-11-2-3-17(14-31)24(33)27-19-8-9-19/h4-7,17,19H,2-3,8-15H2,1H3,(H,27,33)/t17-/m0/s1

InChI Key

HDUSJYONTCJXBQ-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27466753

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.534

Distribution Coefficient, logD

1.534

Water Solubility, LogSw

-2.69

Polar Surface Area

72.090

Acid Dissociation Constant (pKa)

13.13

Base Dissociation Constant (pKb)

3.51

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.00

L632-1083 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Soluble Diversity Library (15920 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with L632-1083 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L632-1083?
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What is the minimum amount of L632-1083 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L632-1083
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L632-1083
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L632-1083 available by request