L632-1148 Screening compound: N-cyclopropyl-1-{5-[2-(4-fluorophenoxy)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}piperidine-3-carboxamide

L632-1148 Screening compound: N-cyclopropyl-1-{5-[2-(4-fluorophenoxy)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}piperidine-3-carboxamide
L632-1148 Screening compound: N-cyclopropyl-1-{5-[2-(4-fluorophenoxy)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L632-1148
N-cyclopropyl-1-{5-[2-(4-fluorophenoxy)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L632-1148

Molecular Formula

C25H30FN5O4 (C25 H30 FN5 O4)

Compound Name

N-cyclopropyl-1-{5-[2-(4-fluorophenoxy)acetyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}piperidine-3-carboxamide

IUPAC name

N-cyclopropyl-1-{5-[2-(4-fluorophenoxy)acetyl]-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridine-3-carbonyl}piperidine-3-carboxamide

SMILES

Cn1nc(C(N(CCC2)CC2C(NC2CC2)=O)=O)c(C2)c1CCN2C(COc(cc1)ccc1F)=O

InChI

InChI=1S/C25H30FN5O4/c1-29-21-10-12-30(22(32)15-35-19-8-4-17(26)5-9-19)14-20(21)23(28-29)25(34)31-11-2-3-16(13-31)24(33)27-18-6-7-18/h4-5,8-9,16,18H,2-3,6-7,10-15H2,1H3,(H,27,33)/t16-/m0/s1

InChI Key

UUFZZWHUOCIECU-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27466766

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

483.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.470

Distribution Coefficient, logD

0.470

Water Solubility, LogSw

-1.97

Polar Surface Area

79.589

Acid Dissociation Constant (pKa)

13.13

Base Dissociation Constant (pKb)

10.75

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.00

L632-1148 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

New Agro Library (44492 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Mimetics
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L632-1148 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L632-1148?
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What is the minimum amount of L632-1148 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L632-1148
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L632-1148
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L632-1148 available by request