L632-1189 Screening compound: 1-{1-methyl-5-[2-(4-methylphenyl)acetyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}-N-phenylpiperidine-3-carboxamide

L632-1189 Screening compound: 1-{1-methyl-5-[2-(4-methylphenyl)acetyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}-N-phenylpiperidine-3-carboxamide
L632-1189 Screening compound: 1-{1-methyl-5-[2-(4-methylphenyl)acetyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}-N-phenylpiperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L632-1189
1-{1-methyl-5-[2-(4-methylphenyl)acetyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}-N-phenylpiperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L632-1189

Molecular Formula

C29H33N5O3 (C29 H33 N5 O3)

Compound Name

1-{1-methyl-5-[2-(4-methylphenyl)acetyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}-N-phenylpiperidine-3-carboxamide

IUPAC name

1-{1-methyl-5-[2-(4-methylphenyl)acetyl]-1H4H5H6H7H-pyrazolo[43-c]pyridine-3-carbonyl}-N-phenylpiperidine-3-carboxamide

SMILES

Cc1ccc(CC(N(CC2)Cc3c2n(C)nc3C(N(CCC2)CC2C(Nc2ccccc2)=O)=O)=O)cc1

InChI

InChI=1S/C29H33N5O3/c1-20-10-12-21(13-11-20)17-26(35)33-16-14-25-24(19-33)27(31-32(25)2)29(37)34-15-6-7-22(18-34)28(36)30-23-8-4-3-5-9-23/h3-5,8-13,22H,6-7,14-19H2,1-2H3,(H,30,36)/t22-/m0/s1

InChI Key

TURSSPFFBYSKMX-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD27466777

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.61

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.369

Distribution Coefficient, logD

2.369

Water Solubility, LogSw

-2.76

Polar Surface Area

70.712

Acid Dissociation Constant (pKa)

12.00

Base Dissociation Constant (pKb)

3.51

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.90

L632-1189 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Proteases
  • Others
Mechanism of action:
  • PPI modulators
  • Epigenetic
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with L632-1189 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L632-1189?
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What is the minimum amount of L632-1189 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L632-1189
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L632-1189
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L632-1189 available by request