L634-0268 Screening compound: N-({1-[(3-chlorophenyl)methyl]piperidin-4-yl}methyl)indolizine-2-carboxamide

L634-0268 Screening compound: N-({1-[(3-chlorophenyl)methyl]piperidin-4-yl}methyl)indolizine-2-carboxamide
L634-0268 Screening compound: N-({1-[(3-chlorophenyl)methyl]piperidin-4-yl}methyl)indolizine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L634-0268
N-({1-[(3-chlorophenyl)methyl]piperidin-4-yl}methyl)indolizine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L634-0268

Molecular Formula

C22H24ClN3O (C22 H24 ClN3 O)

Compound Name

N-({1-[(3-chlorophenyl)methyl]piperidin-4-yl}methyl)indolizine-2-carboxamide

IUPAC name

N-({1-[(3-chlorophenyl)methyl]piperidin-4-yl}methyl)indolizine-2-carboxamide

SMILES

O=C(c1cn(cccc2)c2c1)NCC1CCN(Cc2cccc(Cl)c2)CC1

InChI

InChI=1S/C22H24ClN3O/c23-20-5-3-4-18(12-20)15-25-10-7-17(8-11-25)14-24-22(27)19-13-21-6-1-2-9-26(21)16-19/h1-6,9,12-13,16-17H,7-8,10-11,14-15H2,(H,24,27)

InChI Key

LTLDSZKMHQKHST-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15132449

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.9

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.521

Distribution Coefficient, logD

2.704

Water Solubility, LogSw

-4.56

Polar Surface Area

29.347

Acid Dissociation Constant (pKa)

14.15

Base Dissociation Constant (pKb)

9.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

L634-0268 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with L634-0268 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L634-0268?
Check Price and Availability of L634-0268, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L634-0268 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L634-0268
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L634-0268
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L634-0268 available by request