L637-0749 Screening compound: N-[3-(azepan-1-yl)propyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide

L637-0749 Screening compound: N-[3-(azepan-1-yl)propyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide
L637-0749 Screening compound: N-[3-(azepan-1-yl)propyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L637-0749
N-[3-(azepan-1-yl)propyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L637-0749

Molecular Formula

C22H31N5O2S (C22 H31 N5 O2 S)

Compound Name

N-[3-(azepan-1-yl)propyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide

IUPAC name

N-[3-(azepan-1-yl)propyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-13-thiazole-4-carboxamide

SMILES

O=C(c1csc(-c2cc(N3CCOCC3)ncc2)n1)NCCCN1CCCCCC1

InChI

InChI=1S/C22H31N5O2S/c28-21(24-7-5-11-26-9-3-1-2-4-10-26)19-17-30-22(25-19)18-6-8-23-20(16-18)27-12-14-29-15-13-27/h6,8,16-17H,1-5,7,9-15H2,(H,24,28)

InChI Key

GRGVBODBUISMEW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27467002

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.59

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.383

Distribution Coefficient, logD

0.813

Water Solubility, LogSw

-3.67

Polar Surface Area

58.413

Acid Dissociation Constant (pKa)

15.54

Base Dissociation Constant (pKb)

9.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

59.10

L637-0749 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L637-0749 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L637-0749?
Check Price and Availability of L637-0749, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L637-0749 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L637-0749
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L637-0749
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L637-0749 available by request