L637-0788 Screening compound: N-{[4-(methylsulfanyl)phenyl]methyl}-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide

L637-0788 Screening compound: N-{[4-(methylsulfanyl)phenyl]methyl}-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide
L637-0788 Screening compound: N-{[4-(methylsulfanyl)phenyl]methyl}-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L637-0788
N-{[4-(methylsulfanyl)phenyl]methyl}-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L637-0788

Molecular Formula

C21H22N4O2S2 (C21 H22 N4 O2 S2)

Compound Name

N-{[4-(methylsulfanyl)phenyl]methyl}-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide

IUPAC name

N-{[4-(methylsulfanyl)phenyl]methyl}-2-[2-(morpholin-4-yl)pyridin-4-yl]-13-thiazole-4-carboxamide

SMILES

CSc1ccc(CNC(c2csc(-c3cc(N4CCOCC4)ncc3)n2)=O)cc1

InChI

InChI=1S/C21H22N4O2S2/c1-28-17-4-2-15(3-5-17)13-23-20(26)18-14-29-21(24-18)16-6-7-22-19(12-16)25-8-10-27-11-9-25/h2-7,12,14H,8-11,13H2,1H3,(H,23,26)

InChI Key

OAWXQMPVTVPATM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27467009

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.56

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.304

Distribution Coefficient, logD

4.296

Water Solubility, LogSw

-4.21

Polar Surface Area

54.258

Acid Dissociation Constant (pKa)

13.03

Base Dissociation Constant (pKb)

5.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

L637-0788 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

PI3K-Targeted Library (17255 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with L637-0788 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L637-0788?
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What is the minimum amount of L637-0788 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L637-0788
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L637-0788
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L637-0788 available by request