L637-0790 Screening compound: N-[(2,3-dimethoxyphenyl)methyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide

L637-0790 Screening compound: N-[(2,3-dimethoxyphenyl)methyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide
L637-0790 Screening compound: N-[(2,3-dimethoxyphenyl)methyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L637-0790
N-[(2,3-dimethoxyphenyl)methyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L637-0790

Molecular Formula

C22H24N4O4S (C22 H24 N4 O4 S)

Compound Name

N-[(2,3-dimethoxyphenyl)methyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide

IUPAC name

N-[(23-dimethoxyphenyl)methyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-13-thiazole-4-carboxamide

SMILES

COc1cccc(CNC(c2csc(-c3cc(N4CCOCC4)ncc3)n2)=O)c1OC

InChI

InChI=1S/C22H24N4O4S/c1-28-18-5-3-4-16(20(18)29-2)13-24-21(27)17-14-31-22(25-17)15-6-7-23-19(12-15)26-8-10-30-11-9-26/h3-7,12,14H,8-11,13H2,1-2H3,(H,24,27)

InChI Key

JTGCPLBYAUFVPA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27467011

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

440.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.726

Distribution Coefficient, logD

3.718

Water Solubility, LogSw

-3.97

Polar Surface Area

69.605

Acid Dissociation Constant (pKa)

13.53

Base Dissociation Constant (pKb)

5.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

L637-0790 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L637-0790 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L637-0790?
Check Price and Availability of L637-0790, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L637-0790 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L637-0790
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L637-0790
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L637-0790 available by request