L639-0234 Screening compound: N-[(2-chloro-4-fluorophenyl)methyl]-1-{6H-thieno[2,3-b]pyrrole-5-carbonyl}piperidine-4-carboxamide

L639-0234 Screening compound: N-[(2-chloro-4-fluorophenyl)methyl]-1-{6H-thieno[2,3-b]pyrrole-5-carbonyl}piperidine-4-carboxamide
L639-0234 Screening compound: N-[(2-chloro-4-fluorophenyl)methyl]-1-{6H-thieno[2,3-b]pyrrole-5-carbonyl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L639-0234
N-[(2-chloro-4-fluorophenyl)methyl]-1-{6H-thieno[2,3-b]pyrrole-5-carbonyl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L639-0234

Molecular Formula

C20H19ClFN3O2S (C20 H19 ClFN3 O2 S)

Compound Name

N-[(2-chloro-4-fluorophenyl)methyl]-1-{6H-thieno[2,3-b]pyrrole-5-carbonyl}piperidine-4-carboxamide

IUPAC name

N-[(2-chloro-4-fluorophenyl)methyl]-1-{6H-thieno[23-b]pyrrole-5-carbonyl}piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1C(c([nH]1)cc2c1scc2)=O)NCc(ccc(F)c1)c1Cl

InChI

InChI=1S/C20H19ClFN3O2S/c21-16-10-15(22)2-1-14(16)11-23-18(26)12-3-6-25(7-4-12)20(27)17-9-13-5-8-28-19(13)24-17/h1-2,5,8-10,12,24H,3-4,6-7,11H2,(H,23,26)

InChI Key

IEZIJOFXEXMLJE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15132556

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.91

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.711

Distribution Coefficient, logD

3.711

Water Solubility, LogSw

-4.07

Polar Surface Area

52.039

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

-0.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

L639-0234 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

PLpro Library (6343 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L639-0234 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L639-0234?
Check Price and Availability of L639-0234, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L639-0234 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L639-0234
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L639-0234
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L639-0234 available by request