L644-0467 Screening compound: 1-[4-(acetylamino)phenyl]-N~3~-(4-fluorobenzyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide

L644-0467 Screening compound: 1-[4-(acetylamino)phenyl]-N~3~-(4-fluorobenzyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
L644-0467 Screening compound: 1-[4-(acetylamino)phenyl]-N~3~-(4-fluorobenzyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L644-0467
1-[4-(acetylamino)phenyl]-N~3~-(4-fluorobenzyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L644-0467

Molecular Formula

C21H18FN3O3 (C21 H18 FN3 O3)

Compound Name

1-[4-(acetylamino)phenyl]-N~3~-(4-fluorobenzyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide

IUPAC name

n/a

SMILES

CC(Nc(cc1)ccc1N(C=CC=C1C(NCc(cc2)ccc2F)=O)C1=O)=O

InChI

InChI=1S/C21H18FN3O3/c1-14(26)24-17-8-10-18(11-9-17)25-12-2-3-19(21(25)28)20(27)23-13-15-4-6-16(22)7-5-15/h2-12H,13H2,1H3,(H,23,27)(H,24,26)

InChI Key

BLEDHQPRCAXNGW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27467166

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.766

Distribution Coefficient, logD

1.762

Water Solubility, LogSw

-2.23

Polar Surface Area

63.182

Acid Dissociation Constant (pKa)

9.44

Base Dissociation Constant (pKb)

-7.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

L644-0467 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Integrin Receptors Targeted library (1715 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Others
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L644-0467 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L644-0467?
Check Price and Availability of L644-0467, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L644-0467 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L644-0467
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L644-0467
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L644-0467 available by request