L650-0984 Screening compound: 2-[(2,4-dimethylphenyl)amino]-N-[(pyridin-3-yl)methyl]-1,3-thiazole-4-carboxamide

L650-0984 Screening compound: 2-[(2,4-dimethylphenyl)amino]-N-[(pyridin-3-yl)methyl]-1,3-thiazole-4-carboxamide
L650-0984 Screening compound: 2-[(2,4-dimethylphenyl)amino]-N-[(pyridin-3-yl)methyl]-1,3-thiazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L650-0984
2-[(2,4-dimethylphenyl)amino]-N-[(pyridin-3-yl)methyl]-1,3-thiazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L650-0984

Molecular Formula

C18H18N4OS (C18 H18 N4 OS)

Compound Name

2-[(2,4-dimethylphenyl)amino]-N-[(pyridin-3-yl)methyl]-1,3-thiazole-4-carboxamide

IUPAC name

2-[(24-dimethylphenyl)amino]-N-[(pyridin-3-yl)methyl]-13-thiazole-4-carboxamide

SMILES

Cc(cc1)cc(C)c1Nc1nc(C(NCc2cnccc2)=O)cs1

InChI

InChI=1S/C18H18N4OS/c1-12-5-6-15(13(2)8-12)21-18-22-16(11-24-18)17(23)20-10-14-4-3-7-19-9-14/h3-9,11H,10H2,1-2H3,(H,20,23)(H,21,22)

InChI Key

MRJMMOYFYKECGK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27467455

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

338.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.754

Distribution Coefficient, logD

3.754

Water Solubility, LogSw

-3.53

Polar Surface Area

52.431

Acid Dissociation Constant (pKa)

13.22

Base Dissociation Constant (pKb)

3.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

L650-0984 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases

References: we are preparing a list of scientific research reports with L650-0984 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L650-0984?
Check Price and Availability of L650-0984, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L650-0984 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L650-0984
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L650-0984
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L650-0984 available by request