L653-0308 Screening compound: 2-[(3-BROMOPHENYL)FORMAMIDO]-N-[(1,3-THIAZOL-4-YL)METHYL]PROPANAMIDE

L653-0308 Screening compound: 2-[(3-BROMOPHENYL)FORMAMIDO]-N-[(1,3-THIAZOL-4-YL)METHYL]PROPANAMIDE
L653-0308 Screening compound: 2-[(3-BROMOPHENYL)FORMAMIDO]-N-[(1,3-THIAZOL-4-YL)METHYL]PROPANAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L653-0308
2-[(3-BROMOPHENYL)FORMAMIDO]-N-[(1,3-THIAZOL-4-YL)METHYL]PROPANAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L653-0308

Molecular Formula

C14H14BrN3O2S (C14 H14 BrN3 O2 S)

Compound Name

2-[(3-BROMOPHENYL)FORMAMIDO]-N-[(1,3-THIAZOL-4-YL)METHYL]PROPANAMIDE

IUPAC name

n/a

SMILES

CC(C(NCc1cscn1)=O)NC(c1cccc(Br)c1)=O

InChI

InChI=1S/C14H14BrN3O2S/c1-9(13(19)16-6-12-7-21-8-17-12)18-14(20)10-3-2-4-11(15)5-10/h2-5,7-9H,6H2,1H3,(H,16,19)(H,18,20)/t9-/m0/s1

InChI Key

XZSVYBPZEAOBHQ-VIFPVBQESA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.25

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.062

Distribution Coefficient, logD

2.062

Water Solubility, LogSw

-2.71

Polar Surface Area

58.623

Acid Dissociation Constant (pKa)

11.57

Base Dissociation Constant (pKb)

1.89

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

21.40

L653-0308 in Drug Discovery

Included in Screening Libraries

3D Mimetics PPI Library (1617 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

SH2 Library (10483 compounds)

Soluble Diversity Library (15920 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Structure:
  • Mimetics
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with L653-0308 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L653-0308?
Check Price and Availability of L653-0308, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L653-0308 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L653-0308
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L653-0308
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L653-0308 available by request