L657-0190 Screening compound: N-[3-(4-methylpiperazin-1-yl)propyl]-2-(thiophen-2-yl)pyridine-4-carboxamide

L657-0190 Screening compound: N-[3-(4-methylpiperazin-1-yl)propyl]-2-(thiophen-2-yl)pyridine-4-carboxamide
L657-0190 Screening compound: N-[3-(4-methylpiperazin-1-yl)propyl]-2-(thiophen-2-yl)pyridine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L657-0190
N-[3-(4-methylpiperazin-1-yl)propyl]-2-(thiophen-2-yl)pyridine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L657-0190

Molecular Formula

C18H24N4OS (C18 H24 N4 OS)

Compound Name

N-[3-(4-methylpiperazin-1-yl)propyl]-2-(thiophen-2-yl)pyridine-4-carboxamide

IUPAC name

N-[3-(4-methylpiperazin-1-yl)propyl]-2-(thiophen-2-yl)pyridine-4-carboxamide

SMILES

CN1CCN(CCCNC(c2cc(-c3cccs3)ncc2)=O)CC1

InChI

InChI=1S/C18H24N4OS/c1-21-9-11-22(12-10-21)8-3-6-20-18(23)15-5-7-19-16(14-15)17-4-2-13-24-17/h2,4-5,7,13-14H,3,6,8-12H2,1H3,(H,20,23)

InChI Key

OOEATPZVFDBAIK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27467574

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

344.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.556

Distribution Coefficient, logD

0.405

Water Solubility, LogSw

-2.38

Polar Surface Area

41.747

Acid Dissociation Constant (pKa)

13.95

Base Dissociation Constant (pKb)

8.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.40

L657-0190 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L657-0190 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L657-0190?
Check Price and Availability of L657-0190, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L657-0190 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L657-0190
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L657-0190
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L657-0190 available by request