L658-0010 Screening compound: 2-(thiophen-2-yl)-N-[2-(trifluoromethyl)phenyl]pyridine-3-carboxamide

L658-0010 Screening compound: 2-(thiophen-2-yl)-N-[2-(trifluoromethyl)phenyl]pyridine-3-carboxamide
L658-0010 Screening compound: 2-(thiophen-2-yl)-N-[2-(trifluoromethyl)phenyl]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L658-0010
2-(thiophen-2-yl)-N-[2-(trifluoromethyl)phenyl]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L658-0010

Molecular Formula

C17H11F3N2OS (C17 H11 F3 N2 OS)

Compound Name

2-(thiophen-2-yl)-N-[2-(trifluoromethyl)phenyl]pyridine-3-carboxamide

IUPAC name

2-(thiophen-2-yl)-N-[2-(trifluoromethyl)phenyl]pyridine-3-carboxamide

SMILES

O=C(c1cccnc1-c1cccs1)Nc1c(C(F)(F)F)cccc1

InChI

InChI=1S/C17H11F3N2OS/c18-17(19,20)12-6-1-2-7-13(12)22-16(23)11-5-3-9-21-15(11)14-8-4-10-24-14/h1-10H,(H,22,23)

InChI Key

ZGNHQCLTCAYBGL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15132744

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

348.35

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.095

Distribution Coefficient, logD

4.095

Water Solubility, LogSw

-4.49

Polar Surface Area

33.197

Acid Dissociation Constant (pKa)

11.46

Base Dissociation Constant (pKb)

1.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.90

L658-0010 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Agro:
  • Agro
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L658-0010 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L658-0010?
Check Price and Availability of L658-0010, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L658-0010 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L658-0010
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L658-0010
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L658-0010 available by request