L663-0558 Screening compound: 3-{[6-(4-fluorophenyl)pyrimidin-4-yl]oxy}-N-(2-methylpropyl)benzamide

L663-0558 Screening compound: 3-{[6-(4-fluorophenyl)pyrimidin-4-yl]oxy}-N-(2-methylpropyl)benzamide
L663-0558 Screening compound: 3-{[6-(4-fluorophenyl)pyrimidin-4-yl]oxy}-N-(2-methylpropyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L663-0558
3-{[6-(4-fluorophenyl)pyrimidin-4-yl]oxy}-N-(2-methylpropyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L663-0558

Molecular Formula

C21H20FN3O2 (C21 H20 FN3 O2)

Compound Name

3-{[6-(4-fluorophenyl)pyrimidin-4-yl]oxy}-N-(2-methylpropyl)benzamide

IUPAC name

3-{[6-(4-fluorophenyl)pyrimidin-4-yl]oxy}-N-(2-methylpropyl)benzamide

SMILES

CC(C)CNC(c1cccc(Oc2cc(-c(cc3)ccc3F)ncn2)c1)=O

InChI

InChI=1S/C21H20FN3O2/c1-14(2)12-23-21(26)16-4-3-5-18(10-16)27-20-11-19(24-13-25-20)15-6-8-17(22)9-7-15/h3-11,13-14H,12H2,1-2H3,(H,23,26)

InChI Key

UMYJRGVQWBVQMN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28119881

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.033

Distribution Coefficient, logD

4.033

Water Solubility, LogSw

-4.18

Polar Surface Area

51.110

Acid Dissociation Constant (pKa)

14.58

Base Dissociation Constant (pKb)

2.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

L663-0558 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L663-0558 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L663-0558?
Check Price and Availability of L663-0558, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L663-0558 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L663-0558
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L663-0558
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L663-0558 available by request