L673-0161 Screening compound: 2-[4-(5-bromothiophene-2-sulfonamido)phenoxy]-N-(prop-2-en-1-yl)pyridine-3-carboxamide

L673-0161 Screening compound: 2-[4-(5-bromothiophene-2-sulfonamido)phenoxy]-N-(prop-2-en-1-yl)pyridine-3-carboxamide
L673-0161 Screening compound: 2-[4-(5-bromothiophene-2-sulfonamido)phenoxy]-N-(prop-2-en-1-yl)pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L673-0161
2-[4-(5-bromothiophene-2-sulfonamido)phenoxy]-N-(prop-2-en-1-yl)pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L673-0161

Molecular Formula

C19H16BrN3O4S2 (C19 H16 BrN3 O4 S2)

Compound Name

2-[4-(5-bromothiophene-2-sulfonamido)phenoxy]-N-(prop-2-en-1-yl)pyridine-3-carboxamide

IUPAC name

2-[4-(5-bromothiophene-2-sulfonamido)phenoxy]-N-(prop-2-en-1-yl)pyridine-3-carboxamide

SMILES

C=CCNC(c1cccnc1Oc(cc1)ccc1NS(c(s1)ccc1Br)(=O)=O)=O

InChI

InChI=1S/C19H16BrN3O4S2/c1-2-11-21-18(24)15-4-3-12-22-19(15)27-14-7-5-13(6-8-14)23-29(25,26)17-10-9-16(20)28-17/h2-10,12,23H,1,11H2,(H,21,24)

InChI Key

RLPOGTCZWZPDND-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27468376

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

494.39

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.265

Distribution Coefficient, logD

4.259

Water Solubility, LogSw

-4.53

Polar Surface Area

82.986

Acid Dissociation Constant (pKa)

9.26

Base Dissociation Constant (pKb)

0.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

L673-0161 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L673-0161 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L673-0161?
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What is the minimum amount of L673-0161 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L673-0161
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L673-0161
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L673-0161 available by request