L673-0182 Screening compound: N~3~-(2-methoxyethyl)-2-{4-[(5,6,7,8-tetrahydro-2-naphthalenylsulfonyl)amino]phenoxy}nicotinamide

L673-0182 Screening compound: N~3~-(2-methoxyethyl)-2-{4-[(5,6,7,8-tetrahydro-2-naphthalenylsulfonyl)amino]phenoxy}nicotinamide
L673-0182 Screening compound: N~3~-(2-methoxyethyl)-2-{4-[(5,6,7,8-tetrahydro-2-naphthalenylsulfonyl)amino]phenoxy}nicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L673-0182
N~3~-(2-methoxyethyl)-2-{4-[(5,6,7,8-tetrahydro-2-naphthalenylsulfonyl)amino]phenoxy}nicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L673-0182

Molecular Formula

C25H27N3O5S (C25 H27 N3 O5 S)

Compound Name

N~3~-(2-methoxyethyl)-2-{4-[(5,6,7,8-tetrahydro-2-naphthalenylsulfonyl)amino]phenoxy}nicotinamide

IUPAC name

n/a

SMILES

COCCNC(c1cccnc1Oc(cc1)ccc1NS(c1cc(CCCC2)c2cc1)(=O)=O)=O

InChI

InChI=1S/C25H27N3O5S/c1-32-16-15-26-24(29)23-7-4-14-27-25(23)33-21-11-9-20(10-12-21)28-34(30,31)22-13-8-18-5-2-3-6-19(18)17-22/h4,7-14,17,28H,2-3,5-6,15-16H2,1H3,(H,26,29)

InChI Key

PACMGOFSQNOPGC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27468394

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.57

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.488

Distribution Coefficient, logD

4.465

Water Solubility, LogSw

-4.33

Polar Surface Area

90.231

Acid Dissociation Constant (pKa)

8.67

Base Dissociation Constant (pKb)

0.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

L673-0182 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L673-0182 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L673-0182?
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What is the minimum amount of L673-0182 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L673-0182
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L673-0182
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L673-0182 available by request