L679-0629 Screening compound: N-(5-chloro-2-methoxyphenyl)-4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide

L679-0629 Screening compound: N-(5-chloro-2-methoxyphenyl)-4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide
L679-0629 Screening compound: N-(5-chloro-2-methoxyphenyl)-4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L679-0629
N-(5-chloro-2-methoxyphenyl)-4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L679-0629

Molecular Formula

C25H24ClFN6O2 (C25 H24 ClFN6 O2)

Compound Name

N-(5-chloro-2-methoxyphenyl)-4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide

IUPAC name

N-(5-chloro-2-methoxyphenyl)-4-{[3-(3-fluorophenyl)-3H-imidazo[45-b]pyridin-2-yl]methyl}piperazine-1-carboxamide

SMILES

COc(ccc(Cl)c1)c1NC(N1CCN(Cc(n2-c3cc(F)ccc3)nc3c2nccc3)CC1)=O

InChI

InChI=1S/C25H24ClFN6O2/c1-35-22-8-7-17(26)14-21(22)30-25(34)32-12-10-31(11-13-32)16-23-29-20-6-3-9-28-24(20)33(23)19-5-2-4-18(27)15-19/h2-9,14-15H,10-13,16H2,1H3,(H,30,34)

InChI Key

KTLUXMPSXTUJCD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27469285

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

494.96

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.720

Distribution Coefficient, logD

3.718

Water Solubility, LogSw

-4.08

Polar Surface Area

57.735

Acid Dissociation Constant (pKa)

10.70

Base Dissociation Constant (pKb)

4.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

L679-0629 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

PI3K-Targeted Library (17255 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Targets:
  • Proteases
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with L679-0629 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L679-0629?
Check Price and Availability of L679-0629, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L679-0629 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L679-0629
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L679-0629
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L679-0629 available by request