L679-0654 Screening compound: ethyl 2-[(4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carbonyl)amino]propanoate

L679-0654 Screening compound: ethyl 2-[(4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carbonyl)amino]propanoate
L679-0654 Screening compound: ethyl 2-[(4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carbonyl)amino]propanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L679-0654
ethyl 2-[(4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carbonyl)amino]propanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L679-0654

Molecular Formula

C23H27FN6O3 (C23 H27 FN6 O3)

Compound Name

ethyl 2-[(4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carbonyl)amino]propanoate

IUPAC name

ethyl 2-[(4-{[3-(3-fluorophenyl)-3H-imidazo[45-b]pyridin-2-yl]methyl}piperazine-1-carbonyl)amino]propanoate

SMILES

CCOC(C(C)NC(N1CCN(Cc2nc3cccnc3n2-c2cccc(F)c2)CC1)=O)=O

InChI

InChI=1S/C23H27FN6O3/c1-3-33-22(31)16(2)26-23(32)29-12-10-28(11-13-29)15-20-27-19-8-5-9-25-21(19)30(20)18-7-4-6-17(24)14-18/h4-9,14,16H,3,10-13,15H2,1-2H3,(H,26,32)/t16-/m0/s1

InChI Key

BCFJORHJUCEUMO-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27469302

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.200

Distribution Coefficient, logD

2.199

Water Solubility, LogSw

-2.69

Polar Surface Area

72.313

Acid Dissociation Constant (pKa)

15.28

Base Dissociation Constant (pKb)

4.82

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

39.10

L679-0654 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

PI3K-Targeted Library (17255 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with L679-0654 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L679-0654?
Check Price and Availability of L679-0654, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L679-0654 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L679-0654
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L679-0654
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L679-0654 available by request