L680-0013 Screening compound: 1-{[3-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-4-(2-methylbenzenesulfonyl)piperazine

L680-0013 Screening compound: 1-{[3-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-4-(2-methylbenzenesulfonyl)piperazine
L680-0013 Screening compound: 1-{[3-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-4-(2-methylbenzenesulfonyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L680-0013
1-{[3-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-4-(2-methylbenzenesulfonyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L680-0013

Molecular Formula

C25H27N5O3S (C25 H27 N5 O3 S)

Compound Name

1-{[3-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-4-(2-methylbenzenesulfonyl)piperazine

IUPAC name

1-{[3-(4-methoxyphenyl)-3H-imidazo[45-b]pyridin-2-yl]methyl}-4-(2-methylbenzenesulfonyl)piperazine

SMILES

Cc(cccc1)c1S(N1CCN(Cc(n2-c(cc3)ccc3OC)nc3c2nccc3)CC1)(=O)=O

InChI

InChI=1S/C25H27N5O3S/c1-19-6-3-4-8-23(19)34(31,32)29-16-14-28(15-17-29)18-24-27-22-7-5-13-26-25(22)30(24)20-9-11-21(33-2)12-10-20/h3-13H,14-18H2,1-2H3

InChI Key

ROYGODQMTZVNGU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27469310

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

477.59

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.046

Distribution Coefficient, logD

3.045

Water Solubility, LogSw

-3.12

Polar Surface Area

64.588

Acid Dissociation Constant (pKa)

27.12

Base Dissociation Constant (pKb)

4.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

L680-0013 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L680-0013 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L680-0013?
Check Price and Availability of L680-0013, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L680-0013 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L680-0013
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L680-0013
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L680-0013 available by request