L680-0108 Screening compound: 1-(2,4-dimethylbenzenesulfonyl)-4-{[3-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine

L680-0108 Screening compound: 1-(2,4-dimethylbenzenesulfonyl)-4-{[3-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine
L680-0108 Screening compound: 1-(2,4-dimethylbenzenesulfonyl)-4-{[3-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L680-0108
1-(2,4-dimethylbenzenesulfonyl)-4-{[3-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L680-0108

Molecular Formula

C25H26FN5O2S (C25 H26 FN5 O2 S)

Compound Name

1-(2,4-dimethylbenzenesulfonyl)-4-{[3-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine

IUPAC name

1-(24-dimethylbenzenesulfonyl)-4-{[3-(4-fluorophenyl)-3H-imidazo[45-b]pyridin-2-yl]methyl}piperazine

SMILES

Cc(cc1)cc(C)c1S(N1CCN(Cc(n2-c(cc3)ccc3F)nc3c2nccc3)CC1)(=O)=O

InChI

InChI=1S/C25H26FN5O2S/c1-18-5-10-23(19(2)16-18)34(32,33)30-14-12-29(13-15-30)17-24-28-22-4-3-11-27-25(22)31(24)21-8-6-20(26)7-9-21/h3-11,16H,12-15,17H2,1-2H3

InChI Key

AZVCCMRMRGUHPK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15133215

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.58

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.809

Distribution Coefficient, logD

3.808

Water Solubility, LogSw

-3.77

Polar Surface Area

57.045

Acid Dissociation Constant (pKa)

27.12

Base Dissociation Constant (pKb)

4.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

L680-0108 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L680-0108 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L680-0108?
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What is the minimum amount of L680-0108 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L680-0108
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L680-0108
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L680-0108 available by request