L683-0372 Screening compound: N~1~-(2-chlorophenyl)-2-{[6-methyl-4-(4-methylbenzyl)-5-oxo-5,6-dihydro-4H-pyrazolo[3,4-e][1,2,4]triazolo[4,3-a]pyrimidin-1-yl]sulfanyl}acetamide
Chemical Structure Depiction of ChemDiv screening compound L683-0372
N~1~-(2-chlorophenyl)-2-{[6-methyl-4-(4-methylbenzyl)-5-oxo-5,6-dihydro-4H-pyrazolo[3,4-e][1,2,4]triazolo[4,3-a]pyrimidin-1-yl]sulfanyl}acetamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
L683-0372
Molecular Formula
C23H20ClN7O2S (C23 H20 ClN7 O2 S)
Compound Name
N~1~-(2-chlorophenyl)-2-{[6-methyl-4-(4-methylbenzyl)-5-oxo-5,6-dihydro-4H-pyrazolo[3,4-e][1,2,4]triazolo[4,3-a]pyrimidin-1-yl]sulfanyl}acetamide
IUPAC name
N-(2-chlorophenyl)-2-({5-methyl-8-[(4-methylphenyl)methyl]-7-oxo-14581011-hexaazatricyclo[7.3.0.0^{26}]dodeca-2(6)3911-tetraen-12-yl}sulfanyl)acetamide
SMILES
Cc1ccc(CN(c(n2-c3c4n(C)nc3)nnc2SCC(Nc(cccc2)c2Cl)=O)C4=O)cc1
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
493.98
Hydrogen Bond Acceptors Count
8.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
7.00
Number of Nitrogen and Oxygen Atoms
9
Partition Coefficient, logP
3.024
Distribution Coefficient, logD
3.024
Water Solubility, LogSw
-3.35
Polar Surface Area
75.891
Acid Dissociation Constant (pKa)
11.00
Base Dissociation Constant (pKb)
0.51
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
17.40
L683-0372 in Drug Discovery
Included in Screening Libraries
KRAS-Targeted Library (16000 compounds)
PI3K-Targeted Library (17255 compounds)
Protein-Protein Interaction Library (218420 compounds)
Serine Proteases Inhibitors Library (32732 compounds)
Chemokine Receptor-Targeted Library (18382 compounds)
New Agro Library (44492 compounds)
Included in 1.7M Stock Database
- Cancer
- Digestive system
- Respiratory tract
- Otorhinolaryngologic
- Cancer
- Digestive system
- Respiratory tract
- Otorhinolaryngologic
- Male
- Female
- Hemic and lymphatic
- Skin
- Infections
- Cancer
- Musculoskeletal
- Digestive system
- Respiratory tract
- Male
- Female
- Cardiovascular
- Skin
- Metabolic
- Immune system
- Immune system
- Kinases
- Kinases
- Proteases
- PPI modulators
- Receptor's ligands
- Agro
References: we are preparing a list of scientific research reports with L683-0372 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)