L690-1332 Screening compound: 2-{8-fluoro-3-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-4-oxo-3H,4H,5H-pyrimido[5,4-b]indol-5-yl}-N-[(4-methylphenyl)methyl]acetamide

L690-1332 Screening compound: 2-{8-fluoro-3-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-4-oxo-3H,4H,5H-pyrimido[5,4-b]indol-5-yl}-N-[(4-methylphenyl)methyl]acetamide
L690-1332 Screening compound: 2-{8-fluoro-3-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-4-oxo-3H,4H,5H-pyrimido[5,4-b]indol-5-yl}-N-[(4-methylphenyl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L690-1332
2-{8-fluoro-3-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-4-oxo-3H,4H,5H-pyrimido[5,4-b]indol-5-yl}-N-[(4-methylphenyl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L690-1332

Molecular Formula

C24H21FN6O3 (C24 H21 FN6 O3)

Compound Name

2-{8-fluoro-3-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-4-oxo-3H,4H,5H-pyrimido[5,4-b]indol-5-yl}-N-[(4-methylphenyl)methyl]acetamide

IUPAC name

2-{8-fluoro-3-[(3-methyl-124-oxadiazol-5-yl)methyl]-4-oxo-3H4H5H-pyrimido[54-b]indol-5-yl}-N-[(4-methylphenyl)methyl]acetamide

SMILES

Cc1noc(CN(C=Nc2c3n(CC(NCc4ccc(C)cc4)=O)c(cc4)c2cc4F)C3=O)n1

InChI

InChI=1S/C24H21FN6O3/c1-14-3-5-16(6-4-14)10-26-20(32)11-31-19-8-7-17(25)9-18(19)22-23(31)24(33)30(13-27-22)12-21-28-15(2)29-34-21/h3-9,13H,10-12H2,1-2H3,(H,26,32)

InChI Key

YXGONLKLYNMTJL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27469956

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

460.47

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.667

Distribution Coefficient, logD

2.667

Water Solubility, LogSw

-2.93

Polar Surface Area

80.627

Acid Dissociation Constant (pKa)

12.86

Base Dissociation Constant (pKb)

-1.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

L690-1332 in Drug Discovery

Included in Screening Libraries

Indole Derivatives (10091 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with L690-1332 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L690-1332?
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What is the minimum amount of L690-1332 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L690-1332
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L690-1332
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L690-1332 available by request