L690-1582 Screening compound: 7,8-dimethoxy-3-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-5-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]-3H,4H,5H-pyrimido[5,4-b]indol-4-one

L690-1582 Screening compound: 7,8-dimethoxy-3-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-5-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]-3H,4H,5H-pyrimido[5,4-b]indol-4-one
L690-1582 Screening compound: 7,8-dimethoxy-3-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-5-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]-3H,4H,5H-pyrimido[5,4-b]indol-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L690-1582
7,8-dimethoxy-3-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-5-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]-3H,4H,5H-pyrimido[5,4-b]indol-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L690-1582

Molecular Formula

C24H28N6O5 (C24 H28 N6 O5)

Compound Name

7,8-dimethoxy-3-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-5-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]-3H,4H,5H-pyrimido[5,4-b]indol-4-one

IUPAC name

78-dimethoxy-3-[(3-methyl-124-oxadiazol-5-yl)methyl]-5-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]-3H4H5H-pyrimido[54-b]indol-4-one

SMILES

CC(CC1)CCN1C(Cn(c(cc1OC)c2cc1OC)c1c2N=CN(Cc2nc(C)no2)C1=O)=O

InChI

InChI=1S/C24H28N6O5/c1-14-5-7-28(8-6-14)21(31)12-30-17-10-19(34-4)18(33-3)9-16(17)22-23(30)24(32)29(13-25-22)11-20-26-15(2)27-35-20/h9-10,13-14H,5-8,11-12H2,1-4H3

InChI Key

CNQMPHVNGGLJBG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27469981

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.52

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

1.278

Distribution Coefficient, logD

1.278

Water Solubility, LogSw

-1.73

Polar Surface Area

87.809

Acid Dissociation Constant (pKa)

21.56

Base Dissociation Constant (pKb)

2.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.80

L690-1582 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L690-1582 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L690-1582?
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What is the minimum amount of L690-1582 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L690-1582
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L690-1582
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L690-1582 available by request