L697-0543 Screening compound: 1-(3-chlorophenyl)-4-(3-{[4-(piperidine-1-sulfonyl)-1H-imidazol-1-yl]methyl}-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one

L697-0543 Screening compound: 1-(3-chlorophenyl)-4-(3-{[4-(piperidine-1-sulfonyl)-1H-imidazol-1-yl]methyl}-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one
L697-0543 Screening compound: 1-(3-chlorophenyl)-4-(3-{[4-(piperidine-1-sulfonyl)-1H-imidazol-1-yl]methyl}-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L697-0543
1-(3-chlorophenyl)-4-(3-{[4-(piperidine-1-sulfonyl)-1H-imidazol-1-yl]methyl}-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L697-0543

Molecular Formula

C21H23ClN6O4S (C21 H23 ClN6 O4 S)

Compound Name

1-(3-chlorophenyl)-4-(3-{[4-(piperidine-1-sulfonyl)-1H-imidazol-1-yl]methyl}-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one

IUPAC name

1-(3-chlorophenyl)-4-(3-{[4-(piperidine-1-sulfonyl)-1H-imidazol-1-yl]methyl}-124-oxadiazol-5-yl)pyrrolidin-2-one

SMILES

O=C(CC(C1)c2nc(Cn3cnc(S(N4CCCCC4)(=O)=O)c3)no2)N1c1cccc(Cl)c1

InChI

InChI=1S/C21H23ClN6O4S/c22-16-5-4-6-17(10-16)28-11-15(9-20(28)29)21-24-18(25-32-21)12-26-13-19(23-14-26)33(30,31)27-7-2-1-3-8-27/h4-6,10,13-15H,1-3,7-9,11-12H2/t15-/m1/s1

InChI Key

PJZPLCUNBACYQB-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD27470581

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.97

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.472

Distribution Coefficient, logD

2.472

Water Solubility, LogSw

-3.11

Polar Surface Area

93.205

Acid Dissociation Constant (pKa)

11.48

Base Dissociation Constant (pKb)

2.12

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.90

L697-0543 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L697-0543 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L697-0543?
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What is the minimum amount of L697-0543 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L697-0543
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L697-0543
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L697-0543 available by request