L703-0247 Screening compound: (2E)-3-(4-methylphenyl)-1-{4-[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl}prop-2-en-1-one

L703-0247 Screening compound: (2E)-3-(4-methylphenyl)-1-{4-[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl}prop-2-en-1-one
L703-0247 Screening compound: (2E)-3-(4-methylphenyl)-1-{4-[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl}prop-2-en-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L703-0247
(2E)-3-(4-methylphenyl)-1-{4-[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl}prop-2-en-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L703-0247

Molecular Formula

C24H25N3O2 (C24 H25 N3 O2)

Compound Name

(2E)-3-(4-methylphenyl)-1-{4-[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl}prop-2-en-1-one

IUPAC name

(2E)-3-(4-methylphenyl)-1-{4-[5-(4-methylphenyl)-124-oxadiazol-3-yl]piperidin-1-yl}prop-2-en-1-one

SMILES

Cc1ccc(/C=C/C(N(CC2)CCC2c2noc(-c3ccc(C)cc3)n2)=O)cc1

InChI

InChI=1S/C24H25N3O2/c1-17-3-7-19(8-4-17)9-12-22(28)27-15-13-20(14-16-27)23-25-24(29-26-23)21-10-5-18(2)6-11-21/h3-12,20H,13-16H2,1-2H3

InChI Key

KSFIANWRHWJLKR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15133415

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.198

Distribution Coefficient, logD

5.198

Water Solubility, LogSw

-5.08

Polar Surface Area

47.765

Acid Dissociation Constant (pKa)

26.55

Base Dissociation Constant (pKb)

3.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

L703-0247 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with L703-0247 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L703-0247?
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What is the minimum amount of L703-0247 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L703-0247
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L703-0247
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L703-0247 available by request