L707-0848 Screening compound: 1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-7-[(4-methylpiperidin-1-yl)sulfonyl]-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one

L707-0848 Screening compound: 1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-7-[(4-methylpiperidin-1-yl)sulfonyl]-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one
L707-0848 Screening compound: 1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-7-[(4-methylpiperidin-1-yl)sulfonyl]-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L707-0848
1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-7-[(4-methylpiperidin-1-yl)sulfonyl]-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L707-0848

Molecular Formula

C26H31N3O4S (C26 H31 N3 O4 S)

Compound Name

1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-7-[(4-methylpiperidin-1-yl)sulfonyl]-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one

IUPAC name

1-[2-(23-dihydro-1H-indol-1-yl)-2-oxoethyl]-7-[(4-methylpiperidin-1-yl)sulfonyl]-2345-tetrahydro-1H-1-benzazepin-2-one

SMILES

CC(CC1)CCN1S(c(cc1)cc(CCC2)c1N(CC(N(CC1)c3c1cccc3)=O)C2=O)(=O)=O

InChI

InChI=1S/C26H31N3O4S/c1-19-11-14-27(15-12-19)34(32,33)22-9-10-24-21(17-22)6-4-8-25(30)29(24)18-26(31)28-16-13-20-5-2-3-7-23(20)28/h2-3,5,7,9-10,17,19H,4,6,8,11-16,18H2,1H3

InChI Key

FILGJZSYUOQDSK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27472012

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.62

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.852

Distribution Coefficient, logD

3.852

Water Solubility, LogSw

-3.94

Polar Surface Area

63.084

Acid Dissociation Constant (pKa)

21.95

Base Dissociation Constant (pKb)

1.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.20

L707-0848 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with L707-0848 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L707-0848?
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What is the minimum amount of L707-0848 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L707-0848
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L707-0848
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L707-0848 available by request