L708-1962 Screening compound: N-(2,5-difluorophenyl)-2-[6-(3,4-dimethoxyphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamide

L708-1962 Screening compound: N-(2,5-difluorophenyl)-2-[6-(3,4-dimethoxyphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamide
L708-1962 Screening compound: N-(2,5-difluorophenyl)-2-[6-(3,4-dimethoxyphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L708-1962
N-(2,5-difluorophenyl)-2-[6-(3,4-dimethoxyphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L708-1962

Molecular Formula

C21H17F2N3O3S (C21 H17 F2 N3 O3 S)

Compound Name

N-(2,5-difluorophenyl)-2-[6-(3,4-dimethoxyphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamide

IUPAC name

N-(25-difluorophenyl)-2-[6-(34-dimethoxyphenyl)imidazo[21-b][13]thiazol-3-yl]acetamide

SMILES

COc(ccc(-c1cn(c(CC(Nc(cc(cc2)F)c2F)=O)cs2)c2n1)c1)c1OC

InChI

InChI=1S/C21H17F2N3O3S/c1-28-18-6-3-12(7-19(18)29-2)17-10-26-14(11-30-21(26)25-17)9-20(27)24-16-8-13(22)4-5-15(16)23/h3-8,10-11H,9H2,1-2H3,(H,24,27)

InChI Key

ZSBOVHRFDUUXPH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27472249

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

429.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.970

Distribution Coefficient, logD

3.945

Water Solubility, LogSw

-4.07

Polar Surface Area

46.617

Acid Dissociation Constant (pKa)

8.74

Base Dissociation Constant (pKb)

5.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

L708-1962 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L708-1962 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L708-1962?
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What is the minimum amount of L708-1962 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L708-1962
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L708-1962
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L708-1962 available by request