L708-1975 Screening compound: 2-[6-(3,4-dimethoxyphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide

L708-1975 Screening compound: 2-[6-(3,4-dimethoxyphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide
L708-1975 Screening compound: 2-[6-(3,4-dimethoxyphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L708-1975
2-[6-(3,4-dimethoxyphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L708-1975

Molecular Formula

C24H22N4O4S2 (C24 H22 N4 O4 S2)

Compound Name

2-[6-(3,4-dimethoxyphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide

IUPAC name

2-[6-(34-dimethoxyphenyl)imidazo[21-b][13]thiazol-3-yl]-N-(6-ethoxy-13-benzothiazol-2-yl)acetamide

SMILES

CCOc(cc1)cc2c1nc(NC(Cc1csc3nc(-c(cc4)cc(OC)c4OC)cn13)=O)s2

InChI

InChI=1S/C24H22N4O4S2/c1-4-32-16-6-7-17-21(11-16)34-23(25-17)27-22(29)10-15-13-33-24-26-18(12-28(15)24)14-5-8-19(30-2)20(9-14)31-3/h5-9,11-13H,4,10H2,1-3H3,(H,25,27,29)

InChI Key

CARJMDRHGUHREK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27472257

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

494.6

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.016

Distribution Coefficient, logD

5.010

Water Solubility, LogSw

-4.57

Polar Surface Area

64.200

Acid Dissociation Constant (pKa)

11.42

Base Dissociation Constant (pKb)

5.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

L708-1975 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L708-1975 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L708-1975?
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What is the minimum amount of L708-1975 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L708-1975
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L708-1975
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L708-1975 available by request