L708-2383 Screening compound: N-(3,4-dimethylphenyl)-2-[6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamide

L708-2383 Screening compound: N-(3,4-dimethylphenyl)-2-[6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamide
L708-2383 Screening compound: N-(3,4-dimethylphenyl)-2-[6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L708-2383
N-(3,4-dimethylphenyl)-2-[6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L708-2383

Molecular Formula

C23H23N3OS (C23 H23 N3 OS)

Compound Name

N-(3,4-dimethylphenyl)-2-[6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamide

IUPAC name

N-(34-dimethylphenyl)-2-[6-(34-dimethylphenyl)imidazo[21-b][13]thiazol-3-yl]acetamide

SMILES

Cc(cc1)c(C)cc1-c1cn(c(CC(Nc2cc(C)c(C)cc2)=O)cs2)c2n1

InChI

InChI=1S/C23H23N3OS/c1-14-5-7-18(9-16(14)3)21-12-26-20(13-28-23(26)25-21)11-22(27)24-19-8-6-15(2)17(4)10-19/h5-10,12-13H,11H2,1-4H3,(H,24,27)

InChI Key

RKQKPYQIJQQEAG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27472386

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

389.52

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.151

Distribution Coefficient, logD

6.148

Water Solubility, LogSw

-5.30

Polar Surface Area

32.054

Acid Dissociation Constant (pKa)

12.57

Base Dissociation Constant (pKb)

5.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

L708-2383 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L708-2383 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L708-2383?
Check Price and Availability of L708-2383, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L708-2383 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L708-2383
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L708-2383
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L708-2383 available by request