L708-2482 Screening compound: methyl 4-{2-[6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamido}benzoate

L708-2482 Screening compound: methyl 4-{2-[6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamido}benzoate
L708-2482 Screening compound: methyl 4-{2-[6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L708-2482
methyl 4-{2-[6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L708-2482

Molecular Formula

C23H21N3O3S (C23 H21 N3 O3 S)

Compound Name

methyl 4-{2-[6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetamido}benzoate

IUPAC name

methyl 4-{2-[6-(34-dimethylphenyl)imidazo[21-b][13]thiazol-3-yl]acetamido}benzoate

SMILES

Cc(cc1)c(C)cc1-c1cn(c(CC(Nc(cc2)ccc2C(OC)=O)=O)cs2)c2n1

InChI

InChI=1S/C23H21N3O3S/c1-14-4-5-17(10-15(14)2)20-12-26-19(13-30-23(26)25-20)11-21(27)24-18-8-6-16(7-9-18)22(28)29-3/h4-10,12-13H,11H2,1-3H3,(H,24,27)

InChI Key

VATKOVLPWICLHS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27472414

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

419.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.255

Distribution Coefficient, logD

5.251

Water Solubility, LogSw

-4.97

Polar Surface Area

53.228

Acid Dissociation Constant (pKa)

10.82

Base Dissociation Constant (pKb)

5.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

L708-2482 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L708-2482 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L708-2482?
Check Price and Availability of L708-2482, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L708-2482 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L708-2482
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L708-2482
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L708-2482 available by request