L708-2985 Screening compound: 2-[6-(3-bromophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]-1-(4-phenylpiperazin-1-yl)ethan-1-one

L708-2985 Screening compound: 2-[6-(3-bromophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]-1-(4-phenylpiperazin-1-yl)ethan-1-one
L708-2985 Screening compound: 2-[6-(3-bromophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]-1-(4-phenylpiperazin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L708-2985
2-[6-(3-bromophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]-1-(4-phenylpiperazin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L708-2985

Molecular Formula

C23H21BrN4OS (C23 H21 BrN4 OS)

Compound Name

2-[6-(3-bromophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]-1-(4-phenylpiperazin-1-yl)ethan-1-one

IUPAC name

2-[6-(3-bromophenyl)imidazo[21-b][13]thiazol-3-yl]-1-(4-phenylpiperazin-1-yl)ethan-1-one

SMILES

O=C(Cc1csc2nc(-c3cccc(Br)c3)cn12)N(CC1)CCN1c1ccccc1

InChI

InChI=1S/C23H21BrN4OS/c24-18-6-4-5-17(13-18)21-15-28-20(16-30-23(28)25-21)14-22(29)27-11-9-26(10-12-27)19-7-2-1-3-8-19/h1-8,13,15-16H,9-12,14H2

InChI Key

GCMDNPQZIQXELA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27472438

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.42

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.971

Distribution Coefficient, logD

4.971

Water Solubility, LogSw

-4.78

Polar Surface Area

28.558

Acid Dissociation Constant (pKa)

19.92

Base Dissociation Constant (pKb)

4.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

L708-2985 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L708-2985 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L708-2985?
Check Price and Availability of L708-2985, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L708-2985 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L708-2985
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L708-2985
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L708-2985 available by request