L711-0677 Screening compound: 1-(1-{3-methyl-1-phenyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine

L711-0677 Screening compound: 1-(1-{3-methyl-1-phenyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine
L711-0677 Screening compound: 1-(1-{3-methyl-1-phenyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L711-0677
1-(1-{3-methyl-1-phenyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L711-0677

Molecular Formula

C26H29N7OS (C26 H29 N7 OS)

Compound Name

1-(1-{3-methyl-1-phenyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine

IUPAC name

1-(1-{3-methyl-1-phenyl-1H-pyrazolo[34-d][13]thiazol-5-yl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine

SMILES

Cc(c1c2nc(N(CCC3)CC3C(N(CC3)CCN3c3ncccc3)=O)s1)nn2-c1ccccc1

InChI

InChI=1S/C26H29N7OS/c1-19-23-24(33(29-19)21-9-3-2-4-10-21)28-26(35-23)32-13-7-8-20(18-32)25(34)31-16-14-30(15-17-31)22-11-5-6-12-27-22/h2-6,9-12,20H,7-8,13-18H2,1H3/t20-/m0/s1

InChI Key

KOJBCGQBQOCMCU-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD27642208

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.63

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.129

Distribution Coefficient, logD

4.120

Water Solubility, LogSw

-4.16

Polar Surface Area

56.645

Acid Dissociation Constant (pKa)

22.40

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.50

L711-0677 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with L711-0677 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L711-0677?
Check Price and Availability of L711-0677, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L711-0677 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L711-0677
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L711-0677
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L711-0677 available by request