L712-0188 Screening compound: N-(2,3-dimethylphenyl)-4-(2-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}ethyl)piperazine-1-carboxamide

L712-0188 Screening compound: N-(2,3-dimethylphenyl)-4-(2-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}ethyl)piperazine-1-carboxamide
L712-0188 Screening compound: N-(2,3-dimethylphenyl)-4-(2-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}ethyl)piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L712-0188
N-(2,3-dimethylphenyl)-4-(2-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}ethyl)piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L712-0188

Molecular Formula

C22H28N6O (C22 H28 N6 O)

Compound Name

N-(2,3-dimethylphenyl)-4-(2-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}ethyl)piperazine-1-carboxamide

IUPAC name

N-(23-dimethylphenyl)-4-(2-{2-methyl-3H-imidazo[45-b]pyridin-3-yl}ethyl)piperazine-1-carboxamide

SMILES

Cc1nc2cccnc2n1CCN(CC1)CCN1C(Nc1c(C)c(C)ccc1)=O

InChI

InChI=1S/C22H28N6O/c1-16-6-4-7-19(17(16)2)25-22(29)27-13-10-26(11-14-27)12-15-28-18(3)24-20-8-5-9-23-21(20)28/h4-9H,10-15H2,1-3H3,(H,25,29)

InChI Key

ALPXWFZMUGJNKP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27472932

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.826

Distribution Coefficient, logD

2.802

Water Solubility, LogSw

-2.91

Polar Surface Area

49.391

Acid Dissociation Constant (pKa)

13.97

Base Dissociation Constant (pKb)

6.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

L712-0188 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Anti-Aging Library (44940 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with L712-0188 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L712-0188?
Check Price and Availability of L712-0188, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L712-0188 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L712-0188
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L712-0188
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L712-0188 available by request