L712-0497 Screening compound: N-(2-chloro-4-methylphenyl)-4-{2-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}piperazine-1-carboxamide

L712-0497 Screening compound: N-(2-chloro-4-methylphenyl)-4-{2-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}piperazine-1-carboxamide
L712-0497 Screening compound: N-(2-chloro-4-methylphenyl)-4-{2-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L712-0497
N-(2-chloro-4-methylphenyl)-4-{2-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L712-0497

Molecular Formula

C25H26ClN7O (C25 H26 ClN7 O)

Compound Name

N-(2-chloro-4-methylphenyl)-4-{2-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}piperazine-1-carboxamide

IUPAC name

N-(2-chloro-4-methylphenyl)-4-{2-[2-(pyridin-4-yl)-3H-imidazo[45-b]pyridin-3-yl]ethyl}piperazine-1-carboxamide

SMILES

Cc(cc1)cc(Cl)c1NC(N1CCN(CCn2c(-c3ccncc3)nc3cccnc23)CC1)=O

InChI

InChI=1S/C25H26ClN7O/c1-18-4-5-21(20(26)17-18)30-25(34)32-14-11-31(12-15-32)13-16-33-23(19-6-9-27-10-7-19)29-22-3-2-8-28-24(22)33/h2-10,17H,11-16H2,1H3,(H,30,34)

InChI Key

PQHONGDMYIFCKY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15133636

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.98

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.615

Distribution Coefficient, logD

3.610

Water Solubility, LogSw

-3.79

Polar Surface Area

57.771

Acid Dissociation Constant (pKa)

12.02

Base Dissociation Constant (pKb)

5.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

L712-0497 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L712-0497 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L712-0497?
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What is the minimum amount of L712-0497 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L712-0497
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L712-0497
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L712-0497 available by request