L716-0215 Screening compound: methyl 2-[4-({3-[(4-chlorophenyl)sulfanyl]pyrazin-2-yl}oxy)benzamido]benzoate

L716-0215 Screening compound: methyl 2-[4-({3-[(4-chlorophenyl)sulfanyl]pyrazin-2-yl}oxy)benzamido]benzoate
L716-0215 Screening compound: methyl 2-[4-({3-[(4-chlorophenyl)sulfanyl]pyrazin-2-yl}oxy)benzamido]benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L716-0215
methyl 2-[4-({3-[(4-chlorophenyl)sulfanyl]pyrazin-2-yl}oxy)benzamido]benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L716-0215

Molecular Formula

C25H18ClN3O4S (C25 H18 ClN3 O4 S)

Compound Name

methyl 2-[4-({3-[(4-chlorophenyl)sulfanyl]pyrazin-2-yl}oxy)benzamido]benzoate

IUPAC name

methyl 2-[4-({3-[(4-chlorophenyl)sulfanyl]pyrazin-2-yl}oxy)benzamido]benzoate

SMILES

COC(c(cccc1)c1NC(c(cc1)ccc1Oc1nccnc1Sc(cc1)ccc1Cl)=O)=O

InChI

InChI=1S/C25H18ClN3O4S/c1-32-25(31)20-4-2-3-5-21(20)29-22(30)16-6-10-18(11-7-16)33-23-24(28-15-14-27-23)34-19-12-8-17(26)9-13-19/h2-15H,1H3,(H,29,30)

InChI Key

PATHACCZRHKRGJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15133764

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

491.95

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.979

Distribution Coefficient, logD

5.770

Water Solubility, LogSw

-6.14

Polar Surface Area

69.267

Acid Dissociation Constant (pKa)

7.61

Base Dissociation Constant (pKb)

-1.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.00

L716-0215 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with L716-0215 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L716-0215?
Check Price and Availability of L716-0215, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L716-0215 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L716-0215
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L716-0215
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L716-0215 available by request